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What is new in WorkOut 2.5?

Document ID: DQ298
Relevant to following products: WorkOut 2.0 WorkOut 2.5
Document description: What is new in WorkOut 2.5?



This article is for users already familiar with earlier releases of WorkOut 2.0 summarising the most important features to be found in WorkOut 2.5.

Quick Start Wizard

The “Specific Application Wizards” featured in WorkOut 2.0 have been replaced with a single “Quick Start Wizard” to help you get started more quickly.  This new wizard enables you to set up your assays by first collecting the measurement data and then adding the analysis. 
Using this technique greatly simplifies your assay setup as you can now preview the analysis settings with the analysed raw data.  (It is still possible to set up your analysis before measurements if required.)
As before, you can save your settings to a protocol so you can run it again with no further alterations.

Analysis Wizard

The new Analysis Wizard identifies the type of application you are trying to set up and automatically configures groups of transforms and their parameters. This is based on the most common assays in use today.  Parameter modification is made easier with the result previews displayed together, on the same screen.
Unlike the earlier “Specific Application Wizards”, the new Analysis Wizard can be used both before and after measurements have been made and to edit existing parameters.

Independent Example Protocols (IEP)

With IEPs, Dazdaq Solutions can now provide new example protocols with customised user interfaces for specific assays.
These are called “independent” because unlike conventional protocols they are actually independent of any instrument or measurement settings. They can also be very easily modified to work with your connected instrument or to import stored data of a particular format (making assays portable between PCs and instruments).
The IEP helps the user find which protocol to use, by clearly illustrating its functionality with “nice-looking” example raw data and results.  The data can be modified to verify the analysis and preview the results.
There will continue to be new IEPs for popular assays available in the future. You can always contact Dazdaq Solutions to request a specific IEP for your assay.

New and improved transforms

Several transforms have been added and existing transforms modified for increased functionality in assay analysis.  The new transform features include:

  • Highlight
    This allows you to highlight wells in the data views and table, based on defined conditions.
  • Scatter Chart
    This displays the results of your assays in chromatogram or scatter chart form.
  • Standard Curve Fit
    You can now import standards data from an existing file . This permit an assay to reference a curve formed from measurements made previously).  Further enhancements include: Error bars included on the fit, weighted fit, Logit (B/B0), parameter fixing (e.g. define the asymptotes of the four parameters fit as samples on the plate).
  • Kinetic Blank Correction
    Use one or more blank wells to blank correct kinetic measurements on a point by point basis.
  • Kinetic Join
    Join kinetic plots which were measured with two separate reading steps into one for coherent analysis.
  • Kinetic Replicates
    Calculate the mean kinetic plot from replicate samples with kinetic measurements.

GLP

Protocols can be created which require the user to enter customised parameters (such as user ID, lot number) before the assay can be started.  This data is included in the report.  These custom fields can be used to enter parameters which are then referenced in the assay analysis.

Import Table Data
This provides import components of your analysis/reporting from a text file (such as dilution factors, standard concentration values, sample Ids) as part of an automated process.

Save Protocol

The Save Protocol wizard will guide you through the process of saving the result settings to a new protocol.  This new feature can be used to change the settings of a protocol, such as changing the measurement parameters. This makes it possible, for example to change a protocol  from one which imports data, to one which takes measurements with a connected instrument.

Scan Mode

Scan data (where more than one points is read within each well) can be measured or imported, displayed with 3D views, analysed and included in the report.
 





Related articles:
DQ288: Where can I get WorkOut 2.5 from?
Where can I get WorkOut 2.5 from?





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