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Why are the MSE and SS of my Cubic Spline large?

Document ID: DQ024
Relevant to following products: Manta WorkOut 2.0
Document description: How is the MSE and SS of Cubic Spline calculated?



By definition the Cubic Spline goes through all points therefore you may consider that the MSE should be 0.  However, as with the other fits, the software calculates the MSE of each replicate point against the fit, rather than the mean of the replicates in each standard group.  The MSE of the Cubic Spline against the means would be 0 (because the spline goes through all mean points), however the MSE of the replicate points is a more useful measure as it is a measure of the error in the replicates.
 




Related articles:
DQ023: Can I extrapolate with the Cubic Spline?
How to: Allow/disallow extrapolation with a Cubic Spline…

DQ010: My Cubic Spline has a kink in it
How To: Use Cubic Spline with non-linear data…

DQ065: Which curve fit should I use?
How To: Choose a curve fit method...





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